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Methotrexate is administered orally or intramuscularly in doses of 15 mg to 30 mg daily for a 5 day course.
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Full blood counts should be closely monitored before.during and after cheapest methotrexate. If a clinically significant drop in white-cell or platelet count develops.methotrexate should be withdrawn immediately. Patients should be advised to report all symptoms or signs suggestive of infection.
Cheapest methotrexate (tumors/abnormal growths) may very rarely appear during methotrexate use. The drug must be stopped and treatment may be needed. Tell your doctor right away if new lumps/growths occur.
HOW TO USE. Read the Patient Information Leaflet if available from your pharmacist before you start taking methotrexate and each time you get a refill. If you have any questions.ask your doctor or pharmacist.Methotrexate is a strong medication. The dosage and how often you take this medication are based on your medical condition and response to treatment. There are many different dosing schedules for this medication (especially for cancer treatment). Therefore.it is very important that you follow your doctor’s instructions carefully. Take this medication by mouth as directed by your doctor.For the treatment of psoriasis or rheumatoid arthritis.take this medication by mouth as directed by your doctor.usually once a week. It may take up to several months cheapest methotrexate you get the full benefit of this drug.Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster.and your risk of side effects will increase.Since this drug can be absorbed through the skin and lungs and may harm an unborn baby.women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.Drink plenty of fluids while taking this medication unless your doctor tells cheapest methotrexate otherwise. Doing so helps your kidneys to remove the drug from your body and avoid some of the side effects.
nerve problems – confusion.weakness.drowsiness.coordination problems.feeling irritable.headache.neck stiffness.vision problems.loss of movement in any part of your body. or.
The most common adverse reactions of methotrexate are bone marrow suppression and mucosal damage which manifest as ulcerative stomatitis.leucopaenia.nausea and other gastrointestinal disorders. These adverse reactions are generally reversible and corrected in about two weeks after the single cheapest methotrexate of methotrexate has been reduced or dose interval increased and/or calcium folinate is used. Other frequently occurring adverse reactions include e.g. malaise.abnormal fatigue.chills and fever.dizziness and reduced immunity to infections.
The potential for increased hepatotoxicity when methotrexate is administered with other hepatotoxic agents has not been evaluated. However.hepatotoxicity has been reported in such cases. Therefore.patients receiving concomitant therapy with methotrexate and other potential hepatotoxins (e.g..azathioprine.retinoids.sulfa-salazine) should be closely monitored for possible increased risk of hepatotoxicity.
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pregnancy should be avoided if either partner is receiving methotrexate; during and for a minimum of 3 months after therapy for male patients, and during and for at least one ovulatory cycle after therapy for female patients.
